Educational activities

Monthly International Seminar Series on Liver Toxicity and Steatotic Liver Disease and different EASL studio topics for DHILI will be organised at a later stage.

As a proposal within our educational activities, we will be launching from January a series of talks on Liver Toxicity and Steatotic Liver Disease, ONCE monthly, given by international experts in the field. The session outline would be a talk of around 45 min with 15 min left for discussion. Conferences will be held on the 3rd Wednesday of each month at 16.30h (CET) starting from January 17^th 2024.

These international seminar series are the result of an outstanding collaboration between the EASL DHILI Consortium (https://easldhiliconsortium.eu/) and the Halt-RONIN (UKRI-Horizon Europe) https://halt-ronin.com/

The objectives are:

• to improve collaboration between different group experts encompassing clinical investigators, researchers, basic scientists, industry partners and regulators.
• To foster scientific progress by disseminating the latest breakthroughs in research on hepatotoxicity and metabolic dysfunction-associated steatotic liver disease

Dr. Pau Sancho-Bru is Group Leader of the Liver Cell Plasticity and Tissue Repair group at IDIBAPS, and Associate Professor at University of Barcelona. His group is conducting translational research in the field of liver diseases, investigating the role of cell plasticity in wound healing and carcinogenesis. One of the main research interests of his group is assessing the potential of stem cells for biomedical and biotechnological applications and particularly to develop 3D organotypic in vitro systems for disease modeling and drug development.

The talk will introduce the different technologies available to generate patient derived liver organoids and discuss their potential to study liver disease and drug development. It will also show the work being performed in the lab regarding the generation of patient-derived liver organoids from liver needle biopsies. Moreover, the talk will present the results we have obtained showing the potential of these organoids to reproduce patient-specific characteristics and the epithelial compartment of the liver.